2022 ACR/EULAR Takayasu Arteritis Classification Criteria

Weighted 10-item score that classifies imaging-confirmed large-vessel vasculitis as Takayasu arteritis in patients aged 60 or younger at diagnosis — a research classification tool, not a stand-alone diagnosis.

Age at diagnosis (years)

Diagnosis of medium- or large-vessel vasculitis established, with mimics excluded

Imaging evidence of vasculitis in the aorta or branch arteries (CT/catheter/MR angiography, ultrasound, or PET)

Sex

Angina or ischemic cardiac pain (+2)

Arm or leg claudication (+2)

Vascular bruit (aorta, carotid, subclavian, axillary, renal, or iliofemoral artery) (+2)

Reduced or absent pulse in an upper extremity (axillary, brachial, or radial artery) (+2)

Carotid artery abnormality (reduced/absent carotid pulse or carotid tenderness) (+2)

Systolic blood pressure difference between arms ≥ 20 mmHg (+1)

Number of affected arterial territories with luminal damage (of 9: thoracic aorta, abdominal aorta, mesenteric, L/R carotid, L/R subclavian, L/R renal)

Symmetric (bilateral) involvement of a paired arterial territory (carotid, subclavian, or renal) (+1)

Abdominal aorta involvement together with renal or mesenteric artery involvement (+3)