SCORE2 / SCORE2-OP / SCORE2-Diabetes

SCORE2 / SCORE2-OP / SCORE2-Diabetes (ESC 10-Year CVD Risk)

Estimates 10-year fatal and non-fatal cardiovascular risk in apparently healthy adults using the ESC SCORE2 family — SCORE2 (40–69, no diabetes), SCORE2-OP (≥70), and SCORE2-Diabetes (40–69, type 2 diabetes) — calibrated only to the four ESC European risk regions, not validated for non-European populations.

Model

Risk region (ESC European calibration)

Sex

Age (years, 40–89)

Current smoker

Systolic blood pressure (mmHg)

Total cholesterol (mmol/L)

HDL cholesterol (mmol/L)

Age at type 2 diabetes diagnosis (years; SCORE2-Diabetes only)

HbA1c (mmol/mol IFCC; SCORE2-Diabetes only)

eGFR (mL/min/1.73 m²; SCORE2-Diabetes only)