CARG Chemotherapy Toxicity Score (Hurria 2011)

Estimates the risk of severe (grade ≥ 3) chemotherapy toxicity in older adults with cancer about to start treatment, combining patient, tumor, treatment, lab, and geriatric-assessment items to stratify low, medium, or high risk.

Age 72 years or older

Sex (selects hemoglobin threshold)

Cancer type is gastrointestinal or genitourinary

Planned chemotherapy dose

Number of chemotherapy drugs

Hemoglobin (g/dL)

Creatinine clearance (mL/min)

Hearing

Number of falls in the past 6 months

Taking medications

Walking one block

Social activity limited by physical or emotional health